Circadian Dexras 1 in rats: Development, location and responsiveness to light
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F16%3A10332846" target="_blank" >RIV/00216208:11310/16:10332846 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3109/07420528.2015.1120741" target="_blank" >http://dx.doi.org/10.3109/07420528.2015.1120741</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/07420528.2015.1120741" target="_blank" >10.3109/07420528.2015.1120741</a>
Alternative languages
Result language
angličtina
Original language name
Circadian Dexras 1 in rats: Development, location and responsiveness to light
Original language description
Dexras1 has been shown to exhibit clock-dependent rhythm in mice suprachiasmatic nucleus (SCN), and its genetic deletion modulates circadian responses to photic and nonphotic cues. We show that the rhythmic expression of Dexras1 mRNA and protein in rat SCN already oscillates with low amplitude at postnatal day 3 and can be detected as early as embryonic day 20. In contrast, its expression in peripheral tissues is not rhythmic in adult rats either. The Dexras1 protein is expressed predominantly in the dorsomedial part of the SCN and the light pulse has only a limited effect on its expression. Our data provide the descriptive basis for speculation about the Dexras1 involvement in the rat circadian physiology.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chronobiology International
ISSN
0742-0528
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
141-150
UT code for WoS article
000372195100001
EID of the result in the Scopus database
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