Voltammetric and adsorption study of 4-nitrophenyl-triazole-labeled 2'-deoxycytidine and 7-deazaadenosine nucleosides at boron-doped diamond electrode
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F18%3A10378037" target="_blank" >RIV/00216208:11310/18:10378037 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/18:00500229 RIV/61388963:_____/18:00500229 RIV/00216224:14740/18:00101395
Result on the web
<a href="https://doi.org/10.1016/j.jelechem.2018.01.003" target="_blank" >https://doi.org/10.1016/j.jelechem.2018.01.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jelechem.2018.01.003" target="_blank" >10.1016/j.jelechem.2018.01.003</a>
Alternative languages
Result language
angličtina
Original language name
Voltammetric and adsorption study of 4-nitrophenyl-triazole-labeled 2'-deoxycytidine and 7-deazaadenosine nucleosides at boron-doped diamond electrode
Original language description
Electrochemical properties of 4-nitrophenyl triazole labeled 2'-deoxycytidine (dCTRN 2) and 7-deazaadenosine (dA(TRNO2)) were studied using alumina-polished boron doped diamond (BDD) electrode in acetate buffer pH 5.0. Cyclic voltammetry revealed peak-shaped signals for reduction of the nitro group at the potentials of ca -0.6 V (vs. AllAgCl13 mol L-1 KCl reference electrode) and for the hydroxylamine/nitroso pair exhibiting quasireversible electron transfer at potentials comparable with redox processes of other nitro aromatic compounds at BDD electrodes. All electrochemical processes are directed by adsorption. Moreover, ex situ adsorption of dA(TRNO2) and transfer to supporting electrolyte enables its quantitation using square wave voltammetry in small (several microliter) sample volumes after optimization of parameters for the hydroxylamine/nitroso redox couple. Competitive adsorption/desorption at the BDD surface was further studied by cyclic voltammetry with dA(TRNO2) in the presence of electrochemically inactive phenyl triazole 7-deazaadenosine conjugate (dA(TR)), revealing mutual displacement of both compounds at BDD surface. Further, the redox processes of simpler aromatic nitro compounds (4-nitrophenyl acetylene and 2-nitronaphthalene) are strongly affected when the BDD surface is covered by dA(TR).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Electroanalytical Chemistry
ISSN
1572-6657
e-ISSN
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Volume of the periodical
821
Issue of the periodical within the volume
July
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
111-120
UT code for WoS article
000437818600018
EID of the result in the Scopus database
2-s2.0-85042624643