The degree of substitution affects the enantioselectivity of sulfobutylether-beta-cyclodextrin chiral stationary phases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F19%3A10402191" target="_blank" >RIV/00216208:11310/19:10402191 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rkKDEQ0siy" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=rkKDEQ0siy</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elps.201800471" target="_blank" >10.1002/elps.201800471</a>
Alternative languages
Result language
angličtina
Original language name
The degree of substitution affects the enantioselectivity of sulfobutylether-beta-cyclodextrin chiral stationary phases
Original language description
Three chiral stationary phases were prepared by dynamic coating of sulfobutylether-beta-cyclodextrin (SBE-beta-CD) with different degrees of substitution, onto strong anion-exchange stationary phases. The enantioselective potential and stability of newly prepared chiral stationary phases were examined using a set of structurally different chiral analytes. Measurements were performed in RP-HPLC. Mobile phases consisted of methanol/formic acid, pH 2.10, and methanol/10 mM ammonium acetate buffer, pH 4.00, in various volume ratios. SBE-beta-CDs with degrees of substitution (DS) 4, 6.3, and 10 proved suitable for the enantioseparation of 14, 11, and 8 analytes, respectively. The SBE-beta-CD DS 4 based chiral stationary phase enabled the enantioseparation of the nearly all basic and neutral compounds. Chiral stationary phases with higher sulfobutylether-beta-cyclodextrin substitution (especially DS 10) yielded higher enantioresolution values for acidic compounds.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GJ19-18005Y" target="_blank" >GJ19-18005Y: Retention mechanisms of intact glycopeptides in hydrophilic interaction liquid chromatography</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrophoresis
ISSN
0173-0835
e-ISSN
—
Volume of the periodical
40
Issue of the periodical within the volume
15
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
1972-1977
UT code for WoS article
000478096900013
EID of the result in the Scopus database
2-s2.0-85060870034