Analytical determination of oestrogenic endocrine disruptors: the method of choice for wastewater treatment plant effluents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F21%3A10437178" target="_blank" >RIV/00216208:11310/21:10437178 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/21:00547234
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9V2Dqh0aL~" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9V2Dqh0aL~</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1071/EN21028" target="_blank" >10.1071/EN21028</a>
Alternative languages
Result language
angličtina
Original language name
Analytical determination of oestrogenic endocrine disruptors: the method of choice for wastewater treatment plant effluents
Original language description
Two analytical approaches - liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-tandem mass spectrometry (GC-MS/MS) methods - were compared for the simultaneous determination of the 19 most important oestrogenic endocrine disrupting chemicals (EDCs), such as 17 beta-oestradiol, oestrone, 17 alpha-ethinyloestradiol, bisphenol A and triclosan in wastewater treatment plant effluents. To lower the instrument limits of detection (ILODs), a derivatisation step preceded detection in both methods. The stability, sensitivity and ease of use of dansylation (Dns) for LC-MS/MS and trimethylsilylation (TMS) for GC-MS/MS derivatives were evaluated before method validation. TMS derivatisation products were highly unstable over time. Parameters such as susceptibility to matrix effects and the stability of monodansylated and didansylated derivatisation products of phytohormones are discussed. Lower ILODs of highly potent EDCs (0.11 ng mL(-1) for 17 beta-oestradiol, 0.01 ng mL(-1) for 17 alpha-ethinyloestradiol and 0.22 ng mL(-1) for oestrone) and stability of derivatisation products within 7 days were achieved using LC-MS/MS; therefore, further validation of this method at environmentally relevant concentrations was conducted. The method limits of detection (MLODs) met the requirements of the European Union defined in Directive 2008/105/ES for 17 alpha-ethinyloestradiol (0.035 ng L-1) and 17 beta-oestradiol (0.4 ng L-1). Twenty samples of wastewater treatment plant effluent from the Czech Republic were screened using LC-MS/MS. Fifteen of the EDCs were detected in at least one sample. The most abundant EDCs were bisphenol A, with a concentration up to 1107 ng L-1, and triclosan, with a concentration up to 76 ng L-1. No seasonal trend between late spring and autumn samples was observed in the frequency or quantity of analytes.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10511 - Environmental sciences (social aspects to be 5.7)
Result continuities
Project
<a href="/en/project/SS02030008" target="_blank" >SS02030008: Centre of environmental research: Waste management, circular economy and environmetal secutiry</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Chemistry
ISSN
1448-2517
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
4
Country of publishing house
AU - AUSTRALIA
Number of pages
13
Pages from-to
143-155
UT code for WoS article
000673558800001
EID of the result in the Scopus database
2-s2.0-85110590794