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A Silver Nanoparticles-Based Selective and Sensitive Colorimetric Assay for Ciprofloxacin in Biological, Environmental, and Commercial Samples

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10472880" target="_blank" >RIV/00216208:11310/23:10472880 - isvavai.cz</a>

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=T15BHi79Ns" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=T15BHi79Ns</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/chemosensors11020091" target="_blank" >10.3390/chemosensors11020091</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A Silver Nanoparticles-Based Selective and Sensitive Colorimetric Assay for Ciprofloxacin in Biological, Environmental, and Commercial Samples

  • Original language description

    The wide-spread usage of ciprofloxacin (CIP) resulted in its presence in different parts of the ecosystem. Thus, a simple, reliable, on-spot detection method for CIP is required in environmental context. Herein, a colorimetric assay is developed for the detection of CIP based on the branched polyethyleneimine (PEI) conjugated silver nanoparticles (PEI-AgNPs). AgNPs are prepared using PEI as stabilizing agent following a simple one-pot two-phase procedure. The prepared PEI-AgNPs are subsequently used for an efficient and selective detection of CIP. The characteristic yellow colour of PEI-AgNPs changed to colourless when CIP was added which was further confirmed by quenching in the intensity of the SPR (surface plasmon resonance) band (hypochromic shift). The proposed method is efficient for the quantitation of CIP in a linear dynamic range (LDR) of 0.1-200 µM with a limit of detection (LOD) of 0.038 µM, and limit of quantification (LOQ) of 0.12 µM. The developed method is selective, efficient, and sensitive to CIP in the presence of numerous interfering species and in real biological, environmental, and commercial pharmaceutical samples. Excellent performance of the proposed method compared to UV-Vis spectroscopy and UPLC in environmental, biological, and commercial pharmaceutical samples is demonstrated.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemosensors

  • ISSN

    2227-9040

  • e-ISSN

    2227-9040

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    18

  • Pages from-to

    91

  • UT code for WoS article

    000938396500001

  • EID of the result in the Scopus database

    2-s2.0-85148866971