Using Principal Component Analysis to Better Understand G-quadruplexes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10478056" target="_blank" >RIV/00216208:11310/23:10478056 - isvavai.cz</a>
Result on the web
<a href="https://physics.mff.cuni.cz/wds/proc/pdf23/WDS23_12_f4_Sgallova.pdf" target="_blank" >https://physics.mff.cuni.cz/wds/proc/pdf23/WDS23_12_f4_Sgallova.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Using Principal Component Analysis to Better Understand G-quadruplexes
Original language description
G-quadruplexes are noncanonical nucleic acid structures. Their high functional and structural diversity shows the importance of better understanding the relationship among G-quadruplex primary sequence and biochemical function. We are exploring this question in the context of a DNA library with 496 sequences, which we screened for five biochemical properties. We analyzed results using a principal component analysis. It revealed a correlation between multimeric state and biochemical activities.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
WDS'23 Proceedings of Contributed Papers — Physics
ISBN
978-80-7378-503-1
ISSN
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e-ISSN
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Number of pages
8
Pages from-to
94-101
Publisher name
Matfyzpress
Place of publication
Praha
Event location
Praha
Event date
May 30, 2023
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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