Gaining Insight into Large Gene Families with the Aid of Bioinformatic Tools

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F23%3A10478613" target="_blank" >RIV/00216208:11310/23:10478613 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-1-0716-2867-6_13" target="_blank" >https://doi.org/10.1007/978-1-0716-2867-6_13</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-0716-2867-6_13" target="_blank" >10.1007/978-1-0716-2867-6_13</a>

Result language
angličtina
Original language name
Gaining Insight into Large Gene Families with the Aid of Bioinformatic Tools
Original language description
Proteins participating in plant cell morphogenesis are often encoded by large gene families, in some cases comprising paralogs with variable (modular) domain organization, as in the case of the formin (FH2 protein) family of actin nucleators that can have also additional functions. Unravelling the phylogeny of such a complex gene family brings a number of specific challenges but may be crucial for predictions of protein function and for experimental design. Here we present an overview of our "cottage industry" semi-manual bioinformatic approach, based mostly, though not exclusively, on freely available software tools, which we used to obtain insight into the evolutionary history of plant FH2 proteins and some other components of the plant cell morphogenesis apparatus.
Czech name
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Czech description
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Project
<a href="/en/project/GA22-33471S" target="_blank" >GA22-33471S: Class I formins: connecting cytoskeletal and membrane dynamics in the developing root</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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