Bone health: Age-related changes in diaphyseal structural properties among European Holocene humans during the last 9000 years
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F25%3A10504850" target="_blank" >RIV/00216208:11310/25:10504850 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=73dJSisw5r" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=73dJSisw5r</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1126/sciadv.adx7981" target="_blank" >10.1126/sciadv.adx7981</a>
Alternative languages
Result language
angličtina
Original language name
Bone health: Age-related changes in diaphyseal structural properties among European Holocene humans during the last 9000 years
Original language description
Age-related deterioration in bone strength among Western humans has been linked with sedentary lifestyles, but the effect remains debatable. We evaluated aging of diaphyseal strength and cortical bone loss in a European Holocene sample of 1881 adult humeri, femora, and tibiae. Diaphyseal aging did not differ between Early and Late Holocene adults, despite their differences in physical activity. Adult diaphyseal aging was accompanied by the disproportionate rate between a faster increase in the medullary area and an absent or marginal increase in the total area. This indicates that subperiosteal apposition did not fully biomechanically compensate for the medullary expansion. Diaphyseal strength remained unchanged through age in female femora and male diaphyses but declined in female humeri and tibiae. We highlight the importance of postnatal growth to compensate for adult medullary expansion. Diaphyseal aging is critical for the upper limbs, as humeri are more sensitive to aging than femora and tibiae.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/GX21-17092X" target="_blank" >GX21-17092X: The Formation of Multi-ethnic Complex Societies in Early Medieval Moravia. Collective Action Theory and Interdisciplinary Approach</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Science Advances
ISSN
2375-2548
e-ISSN
2375-2548
Volume of the periodical
11
Issue of the periodical within the volume
36
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
eadx7981
UT code for WoS article
001566911500012
EID of the result in the Scopus database
2-s2.0-105015420733