Ellipticine and Ellipticinium-human serum albumin (Elli-HSA) conjugate are cytotoxic and form covalent DNA adducts detected by 32P-postlabelling.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F99%3A00003570" target="_blank" >RIV/00216208:11310/99:00003570 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Ellipticine and Ellipticinium-human serum albumin (Elli-HSA) conjugate are cytotoxic and form covalent DNA adducts detected by 32P-postlabelling.

Original language description

A new mechasnism of action of anticancer drug ellipticine and its conjugate with human serum albumin is described. This mechanism is a formation of covalent DNA adducts in vitro and in cells in culture.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/VS96141" target="_blank" >VS96141: Investigation of molecular architecture and molecular interactions of biologically important proteins and their protein domains</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

1999

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

7th Interantional Symposium on Molecular Aspects of Chemotherapy.

ISBN

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ISSN

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e-ISSN

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Number of pages

1

Pages from-to

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Publisher name

ISMAC

Place of publication

Gdansk

Event location

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Event date

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Type of event by nationality

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UT code for WoS article

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