Template-based prediction of ribosomal RNA secondary structure
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F14%3A10290337" target="_blank" >RIV/00216208:11320/14:10290337 - isvavai.cz</a>
Result on the web
<a href="http://ieeexplore.ieee.org/xpl/articleDetails.jsp?tp=&arnumber=6999394" target="_blank" >http://ieeexplore.ieee.org/xpl/articleDetails.jsp?tp=&arnumber=6999394</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/BIBM.2014.6999394" target="_blank" >10.1109/BIBM.2014.6999394</a>
Alternative languages
Result language
angličtina
Original language name
Template-based prediction of ribosomal RNA secondary structure
Original language description
Determining the structure of ribosomal RNAs (rRNAs) is one of the crucial steps in understanding the process of protein synthesis, for which rRNAs are one of the basic components. Nevertheless, due to extreme technical difficulties, spatial (3D) structures have been resolved experimentally for only 14 organisms. Also, computational prediction of 3D rRNA structure is almost impossible, and prediction of secondary structure (the list of base pairs in the folded RNA), an important intermediate step betweensequence and 3D structure that is used broadly in modeling of RNA structures, is in the case of rRNAs hindered by both extreme sequence length and high structure complexity. Here we present a proof-of-concept for an rRNA secondary structure prediction method that utilizes known structures as structural templates. Our template-based prediction algorithm determines those regions of the sequence for which structure is being predicted that are conserved well enough so that their secondary s
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
IN - Informatics
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Bioinformatics and Biomedicine (BIBM), 2014 IEEE International Conference on
ISBN
978-1-4799-5669-2
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
17-20
Publisher name
IEEE
Place of publication
Neuveden
Event location
Belfast, UK
Event date
Nov 2, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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