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Direct covalent coupling of proteins to nanostructured plasma polymers: a route to tunable cell adhesion

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F15%3A10313692" target="_blank" >RIV/00216208:11320/15:10313692 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/15:00445012

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.apsusc.2015.05.162" target="_blank" >http://dx.doi.org/10.1016/j.apsusc.2015.05.162</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.apsusc.2015.05.162" target="_blank" >10.1016/j.apsusc.2015.05.162</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Direct covalent coupling of proteins to nanostructured plasma polymers: a route to tunable cell adhesion

  • Original language description

    Flat and nanostructured thin films were fabricated by deposition of ultra-thin (<2 nm) layer of hydrocarbon plasma polymer over polished silicon and over a pattern of 8 nm-thick poly( ethylene) islands on silicon. Linker-free radical-based covalent binding of bovine serum albumin and tropoelastin was confirmed for both types of films. The binding capability of albumin was found to be stable over many days of ambient air storage time. Tropoelastin-mediated flat plasma polymers favored adhesion and proliferation of osteoblast-like MG-63 cells. Nanostructured plasma polymers were multi-affine and their hierarchical surface represented an additional barrier for cell attachment.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT13297" target="_blank" >NT13297: Augmentation of biological fixation of titanium implants by biomimetic hydrogel coatings enriched with bioactive compounds: The effect on adhesion and synthetic activity of osteoblasts and cells of immune response. Study in vitro.</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Applied Surface Science

  • ISSN

    0169-4332

  • e-ISSN

  • Volume of the periodical

    351

  • Issue of the periodical within the volume

    Neuveden

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    537-545

  • UT code for WoS article

    000359496600069

  • EID of the result in the Scopus database

    2-s2.0-84949780762