Inhibition of A-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F19%3A10419208" target="_blank" >RIV/00216208:11320/19:10419208 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.bpj.2018.11.2650" target="_blank" >https://doi.org/10.1016/j.bpj.2018.11.2650</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bpj.2018.11.2650" target="_blank" >10.1016/j.bpj.2018.11.2650</a>
Alternative languages
Result language
angličtina
Original language name
Inhibition of A-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends
Original language description
Misfolding of the protein alpha-synuclein (alpha Syn) into amyloid fibrils plays a central role in the development of Parkinson's disease. Most approaches for the inhibition of alpha Syn fibril formation are based on stabilizing the native monomeric form of the protein or destabilizing the fibrillized misfolded form.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů