Drop coating deposition Raman (DCDR) spectroscopy of biologically important molecules

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11320%2F23%3A10467642" target="_blank" >RIV/00216208:11320/23:10467642 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2p_ypaWawP" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2p_ypaWawP</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jrs.6524" target="_blank" >10.1002/jrs.6524</a>

Result language

angličtina

Original language name

Drop coating deposition Raman (DCDR) spectroscopy of biologically important molecules

Original language description

Drop coating deposition Raman (DCDR) spectroscopy introduces a simple and easily accessible approach to studying biologically important molecules and their mixtures. The method is based on drying a small drop of solution or suspension of studied molecules deposited on a special hydrophobic surface. The drying process efficiently accumulates the molecules in the &apos;coffee-ring&apos; or any small pattern from which the Raman spectrum can be measured. In this way, a significant (several orders of magnitude) improvement of the Raman detection sensitivity compared with Raman measurement from solution can be reached. Therefore, a small sample volume (several microliters), as well as a low initial concentration of studied molecules in deposited droplets, are important advantages of the DCDR method over the normal Raman one. Recently, many relevant DCDR applications on biomolecules and related molecules have been reported. The mini-review covers a brief overview of the DCDR method (principle, short history, suitable hydrophobic surfaces and state-of-the-art). It will be followed by a summary of the studies over the last 15-20 years on different biologically important molecules, including proteins, lipids (in the form of liposomes) and small molecules (e.g., porphyrins, anthrax marker dipicolinic acid and food and environmental contaminants). Finally, the application potential and further perspectives of the DCDR method for biomolecular studies will be discussed.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

Project

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Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Raman Spectroscopy

ISSN

0377-0486

e-ISSN

1097-4555

Volume of the periodical

54

Issue of the periodical within the volume

7

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

694-705

UT code for WoS article

000970643900001

EID of the result in the Scopus database

2-s2.0-85152797575