Three weeks of intermittent hypoxic training affect antioxidant enzyme activity and increases lipid peroxidation in cyclists
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11510%2F19%3A10398294" target="_blank" >RIV/00216208:11510/19:10398294 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Sh0kneKIt5" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Sh0kneKIt5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00706-019-02451-1" target="_blank" >10.1007/s00706-019-02451-1</a>
Alternative languages
Result language
angličtina
Original language name
Three weeks of intermittent hypoxic training affect antioxidant enzyme activity and increases lipid peroxidation in cyclists
Original language description
The aim of the present study was to evaluate the influence of intermittent hypoxic training (IHT) on antioxidant status in elite cyclists. Fifteen male, elite cyclists were randomly divided into the IHT group (IHT-G) and a normoxia control group (CG). The subjects in IHT-G exercised under normobaric hypoxia environment (O-2 = 15.2%) at intensity of 95% of the lactate threshold (LT) for 3 weeks, whereas the CG exercised under normoxia with intensity of 100% LT. The following variables were measured: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), reduced glutathione (GSH), uric acid (UA), total antioxidant status (TAS), malondialdehyde (MDA), and creatine kinase (CK). All variables were evaluated at baseline and post-exercise, both at rest and following the progressive exercise test (PT). After 3 weeks of training, significant intragroup differences occurred in MDA, GSH, and TAS values, and in GPX and CK activity. There were also significant changes in IHT-G before the experiment and after the PT in SOD, GPX, and CK activity, and in levels of TAS and MDA. After the 3 weeks of training, and following the PT, there were significant differences in SOD, CAT, GPX, and CK activity as well as in levels of UA and MDA. In the CG, before and after the intervention, and the PT, SOD, CAT, and CK activity as well as UA, TAS, and MDA concentrations were significantly different from resting condition. IHT significantly affects SOD, CAT, and MDA in competitive cyclists. We observed lower antioxidant enzyme activity and higher MDA concentration in the IHT-G compared to the CG. This confirms that exercise under hypoxia generates higher oxidative stress than the same training loads performed under normoxia conditions. [GRAPHICS] .
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30306 - Sport and fitness sciences
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Monatshefte für Chemie - Chemical Monthly
ISSN
0026-9247
e-ISSN
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Volume of the periodical
150
Issue of the periodical within the volume
9
Country of publishing house
AT - AUSTRIA
Number of pages
8
Pages from-to
1703-1710
UT code for WoS article
000482907600021
EID of the result in the Scopus database
2-s2.0-85070199030