The physiological neocerebellar extinction syndrome likely exists for human handedness but not footedness - a study on healthy young adults

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11510%2F25%3A10488054" target="_blank" >RIV/00216208:11510/25:10488054 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=REKD946B-9" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=REKD946B-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.actpsy.2025.104829" target="_blank" >10.1016/j.actpsy.2025.104829</a>

Result language

angličtina

Original language name

The physiological neocerebellar extinction syndrome likely exists for human handedness but not footedness - a study on healthy young adults

Original language description

The cerebellum&apos;s role in motor laterality (handedness and footedness) remains unclear. It is a lateralised organ, and one functional manifestation of this lateralisation might be neocerebellar extinction syndrome, clinically identifiable as minor muscle hypotonia and moderate passivity in the cross-preferred. We studied how physiological neocerebellar extinction syndrome relates to handedness and footedness, measuring damping coefficient and frequency differences during controlled falls via 3D kinematic analysis. Data were collected from the dominant and non-dominant upper and lower extremities of 40 left- and 40 right-side dominant adults (mean age = 24.7 +- 0.92 years). Using a linear mixed model, we found that hand dominance significantly increased hand damping, with the dominant hand showing higher coefficients than the non-dominant hand, regardless of handedness. Footedness and foot dominance had little effect on leg damping individually or combined. The combined impact of right-handedness and dominance on hand frequency was minimal. Similarly, footedness and foot dominance individually didn&apos;t affect leg frequency. However, right-footed, right-dominant individuals exhibited significantly higher leg frequency. Our findings suggest that neocerebellar extinction syndrome is more pronounced in the upper extremities, likely due to different spinocerebellar pathways. Additionally, limb segment characteristics are more significant than neocerebellar extinction syndrome in determining limb oscillation frequency.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30306 - Sport and fitness sciences

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Psychologica

ISSN

0001-6918

e-ISSN

1873-6297

Volume of the periodical

254

Issue of the periodical within the volume

April

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

27

Pages from-to

104829

UT code for WoS article

001441174300001

EID of the result in the Scopus database

2-s2.0-85219363953