Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11510%2F25%3A10497752" target="_blank" >RIV/00216208:11510/25:10497752 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/25:10497752 RIV/00216208:11120/25:43928401 RIV/00064173:_____/25:43928401 RIV/00023001:_____/25:00085772
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GjIvSwC3r7" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=GjIvSwC3r7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2196/67570" target="_blank" >10.2196/67570</a>
Alternative languages
Result language
angličtina
Original language name
Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial
Original language description
This study aims to identify predictive factors for successful weight loss in women with obesity following a structured exercise intervention. Using a two-stage analytical design, including a randomized cross-over trial, the research explores the role of metabolic flexibility, insulin sensitivity, and gut microbiome in predicting fat mass reduction. Preliminary results are expected by 2026 and may inform future personalized lifestyle interventions for obesity and T2D prevention.
Czech name
—
Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30306 - Sport and fitness sciences
Result continuities
Project
<a href="/en/project/NU23-01-00509" target="_blank" >NU23-01-00509: The role of Adipose tissue and Muscle crosstalk in regulation of Metabolic flexibility: Exploration of novel predictors of the lifestyle intervention success in obese</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JMIR Research Protocols
ISSN
1929-0748
e-ISSN
1929-0748
Volume of the periodical
14
Issue of the periodical within the volume
May
Country of publishing house
CA - CANADA
Number of pages
9
Pages from-to
e67570
UT code for WoS article
001488792800001
EID of the result in the Scopus database
2-s2.0-105006766749