All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Mutually potentiating effects of drugs elevating extracellular adenosine and granulocyte colony-stimulating factor on erythropoietic recovery following 5-fluorouracil-induced haematotoxicity in mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00003472" target="_blank" >RIV/00216224:14110/00:00003472 - isvavai.cz</a>

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mutually potentiating effects of drugs elevating extracellular adenosine and granulocyte colony-stimulating factor on erythropoietic recovery following 5-fluorouracil-induced haematotoxicity in mice

  • Original language description

    The ability of drugs increasing the level of extracellular adenosine (dipyridamole, AMP) to activate erythropoiesis (BFU-E in the bone marrow, reticulocytes and RBC in the peripheral blood) when given jointly with G-CSF is described. The observed additivity and synergism of G-CSF with elevated extracellular adenosine in terms of erythropoiesis is an interesting finding with potential implications in clinical practice.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

    —

Result continuities

  • Project

    <a href="/en/project/GA306%2F99%2F0027" target="_blank" >GA306/99/0027: Enhancement of G-CSF action by adenosine signalling: testing of its potential clinical use in murine models</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2000

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Drug Development Research

  • ISSN

    0272-4391

  • e-ISSN

    —

  • Volume of the periodical

    50

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    1

  • Pages from-to

    —

  • UT code for WoS article

    —

  • EID of the result in the Scopus database

    —

Similar results(10)

Elevation of extracellular adenosine mobilizes haematopoietic progenitor cells and granulocytes into peripheral blood and enhances the mobilizing effects of granulocyte colony-stimulating factor.Drugs elevating extracellular adenosine promote regeneration of haematopoietic progenitor cells in severely myeloosuppressed mice: their comparison and joint effects with the granulocyte colony-stimulating factorGranulopoiesis-stimulating effects of combined administration of drugs elevating extracellular level of adenosine and G-CSF in mice exposed to ionizing radiation or cytostatic therapy.