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Antiradical phenolic compounds from Cynara cardunculus

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F00%3A00003561" target="_blank" >RIV/00216224:14110/00:00003561 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Antiradical phenolic compounds from Cynara cardunculus

  • Original language description

    Extracts from artichoke (Cynara scolymus L.) or cardoon (Cynara cardunculus L., Asteraceae), are widely used in phytotherapy as choleretic, hypocholesterolemic and hepatoprotective agents (Kraft, 1997). The cholesterol-lowering effect of artichoke extracts was confirmed by numerous animal experiments and recently by a controlled clinical trial. The possible mechanism of hypocholesterolemic activity involves choleretic action, reduction of cholesterol biosynthesis and inhibition of low density lipoprotein oxidation (Pittler and Ernst, 1998). The antiatherosclerotic and antihepatotoxic activities can be mediated by antioxidative action of the artichoke extract. These activities have been ascribed to the phenolic compounds present in the extract. According to HPLC analysis, the methanol extract of C. cardunculus leaves contained three main phenolic components, 5-caffeoylquinic acid (chlorogenic acid), 1,5-dicaffeoylquinic acid (1,5-DiCQA) and flavonoid luteolin-7-O-glucoside. However, caf

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA303%2F00%2FD062" target="_blank" >GA303/00/D062: Bioavailability and mechanism of antioxidant activity of phenolic acids and lignans</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2000

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    In Polyphenols Communication 2000. XX th International Conference on Polyphenols

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

  • Publisher name

    S.Martens, D.Treutter, G.Forkmann, str.425

  • Place of publication

    Freising-Weihenstephan, BRD

  • Event location

  • Event date

  • Type of event by nationality

  • UT code for WoS article