CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F01%3A00004338" target="_blank" >RIV/00216224:14110/01:00004338 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
Original language description
The objectives of the study were (i) to identify morphologically distinct stages in the cell division cycle of C. neoformans, (ii) to identify microtubular and actin components of the cytoskeleton and (iii) to investigate the effect of two cytoskeletal inhibitors, Cytochalasin D and methylbenzimidazol-2-yl carbamate (MBC), on cell proliferation and potential cell death. Both interphase and M-phase were found to be characterised each by three distinct morphological stages: mother cell, development of a sterigma-like protrusion and bud emergence, and nuclear migration into the bud and subsequent mitosis, postmitotic phase, cytokinesis and cell separation. F-actin (patches, cables and cytokinetic rings) was similar to the ascomycetous budding yeast; patches accumulated at the apex of the growing sterigma, in the bud and around the septum, but also were evenly distributed in mother cells. Cytoplasmic and spindle microtubules were similar to those in the ascomycetous fission yeast. Cytoplas
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA310%2F00%2F0391" target="_blank" >GA310/00/0391: Cytoskeleton in human pathogenic yeast microorganisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2001
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XXIX.Výrocná konferencia o kvasinkách, Kongresové centrum SAV Smolenice
ISBN
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ISSN
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e-ISSN
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Number of pages
1
Pages from-to
18-18
Publisher name
Chemický ústav Slovenské akademie ved, Bratislava
Place of publication
Bratislava
Event location
Bratislava
Event date
Jan 1, 2001
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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