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Association of gelatinase a (MMP-2) and endothelin-1 gene polymorphism with plaque psoriasis.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F01%3A00005718" target="_blank" >RIV/00216224:14110/01:00005718 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/01:00021139

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Association of gelatinase a (MMP-2) and endothelin-1 gene polymorphism with plaque psoriasis.

  • Original language description

    The aim of the study was to associate two polymorphisms in gelatinase A (MMP-2, C(-722)T) and endothelin-1 (G8002A) with plaque psoriasis. Expansion of dermal microvasculature is a prominent feature of psoriasis. Our results seem to confirm hypothesis that angiogenesis and chronic inflammation, both involved in psoriasis, are codependent, even from genetical point of view. This link could include both augmentations of cellular infiltration and proliferation and overlapping roles of growth factors and cytokines.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of the European Academy of Dermatology and Venerology

  • ISSN

    0926-9959

  • e-ISSN

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    suppl. 2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    1

  • Pages from-to

    237

  • UT code for WoS article

  • EID of the result in the Scopus database