Office blood pressure, heart rate and interleukin-6 gene polymorphism in apparently healthy Czech middle-aged population

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00006403" target="_blank" >RIV/00216224:14110/02:00006403 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Office blood pressure, heart rate and interleukin-6 gene polymorphism in apparently healthy Czech middle-aged population

Original language description

The aim of the study was to assess the existence of association of promoter polymorphism [A (-597)G] in interleukin-6 gene with office systolic and diastolic blood pressures as well as with heart rate in apparently healthy Czech subjects. Another task was to evaluate possible influence of gender, BMI and smoking on these supposed associations. An age- (40-50 years) and sex-matched (F/M=81/89) sample of healthy Czech subjects (n=170,F/M=81/89) without previous personal history of hypertension, other cardiovascular diseases and/ or diabetes was formed. The A (-597) G IL-6 polymorphism was detected by PCR No differences in genotype distribution and/or allelic frequency was found between groups with "low" systolic blood pressure (below 122mm Hg) and "highsystolic blood pressure (above 122 mm Hg). Similarly, no differences in the IL-6 polymorphism were found between"low" (below 88 mm Hg) and "high" (above 88 mm Hg) diastolic blood pressure groups. But, significant differences were observed

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

2002

Issue of the periodical within the volume

in print

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

1

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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