Effects of CB2receptor agonist palmitoylethanolamide and CB2receptor antagonist AM 630 on leukocyte phagocytic activity in mice

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F02%3A00006896" target="_blank" >RIV/00216224:14110/02:00006896 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effects of CB2receptor agonist palmitoylethanolamide and CB2receptor antagonist AM 630 on leukocyte phagocytic activity in mice

Original language description

The cannabinoids are involved in regulation of immune function. This action can be mediated either through cannabinoid receptors which subtypes CB1 and CB2 have been identified on leukocytes, or by non-receptor mechanism not clearly understood yet. The present study investigated th influence of the CB2 receptor agonist palmitoylethanolamide and the CB2 receptor antagonist AM 630 on the cellular immune function on leukocyte phagocytosis. Phagocytic activity of mouse leukocytes was measured in chemiluminescence (CL) assay using zymosan induction of phagocytosis and luminol potentiated of CL in vitro.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Behavioural Pharmacology

ISSN

0955-8810

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

5-6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

2

Pages from-to

507

UT code for WoS article

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EID of the result in the Scopus database

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