The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010238" target="_blank" >RIV/00216224:14110/04:00010238 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice
Original language description
The present study was designed to test a possible effect of selective agonist at cannabinoid CB2 receptor - JWH 015 (JWH) on behavioural sensitization to MET. Behavioural changes were measured in the open field test. MET and combined MET+JWH pretreatments were administered for 7 days to the mice at the doses of 2.5 mg/kg/day and 5 mg/kg/ day, respectively. On the day 8 all mice were given a "challenge dose" of MET 2.5 mg/kg to check a development of sensitization phenomenon. The sensitization to MET hasnot been altered in the case of use of JWH in the pretreatment.
Czech name
Vliv agonisty kanabinoidního receptoru CB2 JWH015 an rozvoj sensitizace k behaviorálnímu účinku metamfetaminu na lokomočně/pátrací aktivitu myší
Czech description
Rozvoj behaviorální sensitizace k metamfetaminovému účinku na lokomoci u myší není alterován premedikací agonistou CNB2 kanabinoidních receptorů JWH015.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Homeostasis in Health and Diseases
ISSN
0960-7560
e-ISSN
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Volume of the periodical
43
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
3
Pages from-to
39-41
UT code for WoS article
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EID of the result in the Scopus database
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