End-to-side anastomosis of peripheral nerve in experimental and clinical model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F04%3A00010574" target="_blank" >RIV/00216224:14110/04:00010574 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/04:00003625
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
End-to-side anastomosis of peripheral nerve in experimental and clinical model
Original language description
The results of 13 patients with end-to-side anastomosis of the axillary nerve to various donor nerves were presented. The results were evaluated by means of functional and electrophysiological methods following avulsion and subsequent reconstruction of the brachial plexus. End-to-side anastomosis of the rat musculocutaneus nerve (n=12) with the ulnar one was used in the experimental model. The retrograde tracers were applied to prove the reinnervation. Fair and good results were achieved in neurotization of the axillary nerve in 75% of patients with follow up longer than 24 months. Electrophysiology proved reinnervation in 100% of the patients. The average muscle strength, according to the muscle test, was 3.80. The functional recovery started within 7-12 months postoperatively. Retrograde staining in the experimental model demonstrated the reinnervation of the rat biceps muscles 3 months from end-to-side anastomosis, mainly by collateral reinnervation from the ulnar nerve. The ulnar n
Czech name
End-to-side anastomosa periferního nervu v experimenálním a klinickém modelu
Czech description
Byly prezentovány výsledky 13 pacientů, u kterých byl poškozený n. axillaris spojen end-to-side anastomosou s různými donorovými nervy.

Project
<a href="/en/project/NF6658" target="_blank" >NF6658: Alternative approaches in brachial plexus reconstruction and experimental evaluation of various neurotrophic factors action on direct and collateral reinnervation</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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