Genetic variability in the RAGE gene: Possible implications for nutrigenetics, nutrigenomics and understanding the susceptibility to diabetic complications

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00012419" target="_blank" >RIV/00216224:14110/05:00012419 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Genetic variability in the RAGE gene: Possible implications for nutrigenetics, nutrigenomics and understanding the susceptibility to diabetic complications

Original language description

Complex chemical processes called non-enzymatic glycation and glycoxidation are one of the interesting examples of potentially harmful interaction between nutrition and disease. This review summarizes factors influencing the extent of glycoxidation in health and disease and especially focuses on the role of genetic variability in glycoxidation-related genes in disease and diet-related pathogenesis. Possible interaction between genetic variability in relevant loci and dietary Advanced Glycation End products (AGEs) is considered. As AGEs possess a wide range of chemical and biological effects, the interindividual functional variability in systems dealing with glycoxidation could have a significant nutrigenomic and nutrigenetic consequences.

Czech name

Genetická variabilita v RAGE genu: Možné dsledky pro nutrigenetiku, nutrigenomiku a pochopení genetické dispozice k rozvoji diabetických komplikací

Czech description

Pehledná práce shrnuje dosavadní poznatky podporující roli genetické variability v RAGE genu ve vztahu k rozvoji diabetických komplikací a rovnez možné dsledky této variability pro nutrigenetiku a nutrigenomiku.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecular Nutrition & Food Research

ISSN

1613-4125

e-ISSN

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Volume of the periodical

49

Issue of the periodical within the volume

7

Country of publishing house

DE - GERMANY

Number of pages

10

Pages from-to

700-709

UT code for WoS article

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EID of the result in the Scopus database

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