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Blood Pressure and Baroreflex Sensitivity after Anthracycline Chemotherapy in Childhood with Respect to Fatty Acid Metabolism

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F05%3A00019033" target="_blank" >RIV/00216224:14110/05:00019033 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/05:#0000309

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Blood Pressure and Baroreflex Sensitivity after Anthracycline Chemotherapy in Childhood with Respect to Fatty Acid Metabolism

  • Original language description

    Late effects of caardiotoxic therapy on childhood cancer were studied. Body and circulation parameters were compared in 206 helathy controls, and 97 children and adolescents after antitumour treatment at the age of 11 - 21 years with respect to plasma lipid level. The subjects after antitumour therapy had increased parasympathetic and decreased sympathetic tonic activity together with decreased baroreflex sensitivity. The increase of inter-beat interval variability was neither the result of a primary increase of vasomotor activity nor an increase of baroreflex sensitivity response to changes in blood pressure. We can explain it by increasing parasympathetic control of the heart. The circulatory changes did not bear on obesity, but they were rather a specific effect of tumour disease and antitumou treatment.

  • Czech name

    Krevní tlak a citlivost baroreflexu u dětí a adolescentů po chemoterapii antracykliny vzhledem k metabolismu lipidů

  • Czech description

    Studovali jsme pozdní efekt kardiotoxické terapie dětských nádorových onemocnění. Dětští pacienti po prodělané protinádorové léčbě měli zvýšenou parasympatickou a sníženou sympatickou aktivitu spojenou se sníženou citlivostí baroreflexu.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR8006" target="_blank" >NR8006: Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scripta medica

  • ISSN

    1211-3395

  • e-ISSN

  • Volume of the periodical

    78

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    257-263

  • UT code for WoS article

  • EID of the result in the Scopus database