Blood Pressure and Baroreflex Sensitivity after Anthracycline Chemotherapy in Childhood with Respect to Fatty Acid Metabolism

Result code in IS VaVaI

RIV/00216224:14110/05:00019033 - isvavai.cz

Alternative codes found

RIV/65269705:_____/05:#0000309

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Blood Pressure and Baroreflex Sensitivity after Anthracycline Chemotherapy in Childhood with Respect to Fatty Acid Metabolism

Original language description

Late effects of caardiotoxic therapy on childhood cancer were studied. Body and circulation parameters were compared in 206 helathy controls, and 97 children and adolescents after antitumour treatment at the age of 11 - 21 years with respect to plasma lipid level. The subjects after antitumour therapy had increased parasympathetic and decreased sympathetic tonic activity together with decreased baroreflex sensitivity. The increase of inter-beat interval variability was neither the result of a primary increase of vasomotor activity nor an increase of baroreflex sensitivity response to changes in blood pressure. We can explain it by increasing parasympathetic control of the heart. The circulatory changes did not bear on obesity, but they were rather a specific effect of tumour disease and antitumou treatment.

Czech name

Krevní tlak a citlivost baroreflexu u dětí a adolescentů po chemoterapii antracykliny vzhledem k metabolismu lipidů

Czech description

Studovali jsme pozdní efekt kardiotoxické terapie dětských nádorových onemocnění. Dětští pacienti po prodělané protinádorové léčbě měli zvýšenou parasympatickou a sníženou sympatickou aktivitu spojenou se sníženou citlivostí baroreflexu.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

NR8006: Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scripta medica

ISSN

1211-3395

e-ISSN

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Volume of the periodical

78

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

257-263

UT code for WoS article

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EID of the result in the Scopus database

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