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A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F06%3A00017798" target="_blank" >RIV/00216224:14110/06:00017798 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    čeština

  • Original language name

    A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension.

  • Original language description

    The drug can be administered once a day, if the tough-to-peak ratio (T/P) exceeds 50-66%. The mean T/P of betaxolol hydrochloride was calculated 72,84 +- 33,32% (95% CI, 60,40-85,28%) for systolic BP and 71,57 +-29,35% (95% CI, 60,62-82,53%) for diastolic BP. The mean T/P of metoprolol tartrate was calculated 70,59 +- 31,66% (95% CI, 58,76-82,41%) fo systolic BP and 66,95 +- 31,60% (95% CI, 55,15-78,75%) for diastolic BP. 95% CI - 95% confidence interval. Conclusion: The T/P ratio determined for betaxolol hydrochloride and metoprolol tartrate is higher than 66%. The ratio garatees a satisfactory 24-h effect of both the above mentioned drugs.

  • Czech name

    A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension.

  • Czech description

    The drug can be administered once a day, if the tough-to-peak ratio (T/P) exceeds 50-66%. The mean T/P of betaxolol hydrochloride was calculated 72,84 +- 33,32% (95% CI, 60,40-85,28%) for systolic BP and 71,57 +-29,35% (95% CI, 60,62-82,53%) for diastolic BP. The mean T/P of metoprolol tartrate was calculated 70,59 +- 31,66% (95% CI, 58,76-82,41%) fo systolic BP and 66,95 +- 31,60% (95% CI, 55,15-78,75%) for diastolic BP. 95% CI - 95% confidence interval. Conclusion: The T/P ratio determined for betaxolol hydrochloride and metoprolol tartrate is higher than 66%. The ratio garatees a satisfactory 24-h effect of both the above mentioned drugs.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Blood pressure monitoring

  • ISSN

    1359-5237

  • e-ISSN

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database