Subacute Hypertensive Reversible Leukoencephalopathy - a Case Report

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F08%3A00107022" target="_blank" >RIV/00216224:14110/08:00107022 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

Subakutně probíhající reverzibilní hypertenzní leukoencefalopatie - kazuistika

Original language description

Hypertensive encephalopathy induced by essential or secondary arterial hypertension is characterised by a sudden onset of symptoms pointing to diffuse encephalopathy (headache, nausea, vomiting, vision problems, confusion or epileptic seizures) linked with an increase in blood pressure (BP, hypertensive crisis). in such case, the imaging methods applied, especially magnetic resonance (MR), show leukoencephalopathy. Both clinical symptoms and MR imaging findings are reversible after the blood pressure values have been normalised. We report a case of a 37-year old man who developed non-specific symptoms of encephalopathy over the period of one year (cephalea, vision disorders, behaviour changes, atactic walk). CT and MRI of the patient's brain showed diffuse affection of the white matter of the brain, cerebellum and of the cerebral trunk. Inflammatory, demyelinisating, ischaemic, oncologic, metabolic and toxic aetiologies of leukoencephalopathy were excluded. In spite of absence of anamnestic data on arterial hypertension, and of normotensive values at admission, a hypertension crisis developed and clinical symptoms progressed into a picture of delirium. Blood pressure compensation resulted in the regression of clinical symptoms and a significant attenuation of cardiologic signs of encephalopathy, which was a confirmation of hypertensive etiology of leukoencephalopathy. Subsequently, the presence of chronic idiopathic arterial hypertension was confirmed, and secondary causes of hypertension including phaeochromocytoma were excluded. Hypertensive encephalopathy should be considered also in the case of protracted and fluctuating symptoms of encephalopathy and normal results for current blood pressure measurements.

Czech name

Subakutně probíhající reverzibilní hypertenzní leukoencefalopatie - kazuistika

Czech description

Hypertensive encephalopathy induced by essential or secondary arterial hypertension is characterised by a sudden onset of symptoms pointing to diffuse encephalopathy (headache, nausea, vomiting, vision problems, confusion or epileptic seizures) linked with an increase in blood pressure (BP, hypertensive crisis). in such case, the imaging methods applied, especially magnetic resonance (MR), show leukoencephalopathy. Both clinical symptoms and MR imaging findings are reversible after the blood pressure values have been normalised. We report a case of a 37-year old man who developed non-specific symptoms of encephalopathy over the period of one year (cephalea, vision disorders, behaviour changes, atactic walk). CT and MRI of the patient's brain showed diffuse affection of the white matter of the brain, cerebellum and of the cerebral trunk. Inflammatory, demyelinisating, ischaemic, oncologic, metabolic and toxic aetiologies of leukoencephalopathy were excluded. In spite of absence of anamnestic data on arterial hypertension, and of normotensive values at admission, a hypertension crisis developed and clinical symptoms progressed into a picture of delirium. Blood pressure compensation resulted in the regression of clinical symptoms and a significant attenuation of cardiologic signs of encephalopathy, which was a confirmation of hypertensive etiology of leukoencephalopathy. Subsequently, the presence of chronic idiopathic arterial hypertension was confirmed, and secondary causes of hypertension including phaeochromocytoma were excluded. Hypertensive encephalopathy should be considered also in the case of protracted and fluctuating symptoms of encephalopathy and normal results for current blood pressure measurements.

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE

ISSN

1210-7859

e-ISSN

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Volume of the periodical

71

Issue of the periodical within the volume

6

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

726-731

UT code for WoS article

000261867200013

EID of the result in the Scopus database

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