Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F09%3A00029489" target="_blank" >RIV/00216224:14110/09:00029489 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/09:#0000775

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Phenotype of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance

Original language description

The aim of this study was to find possibilities and limits of multicolour flow cytometry in diagnostics of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) and to identify parameters that could be used to differentiatebetween these two disorders. In bone marrow, the percentage of residual polyclonal CD19+ plasma cells was higher (p&lt;0.001) and the percentage of malignant monoclonal CD56+ plasma cells was lower (p&lt;0.001) in MGUS than in MM. The relative counts ofCD19+ plasma cells permitted unequivocal differentiation of MGUS from all clinical stages of MM. Flow cytometry is relatively quick and effective method for analysis of plasma cells thus immunophenotyping can significantly contribute to the differentialdiagnosis of plasma cell proliferations.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neoplasma

ISSN

0028-2685

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

6

Country of publishing house

SK - SLOVAKIA

Number of pages

7

Pages from-to

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UT code for WoS article

000270369200011

EID of the result in the Scopus database

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