Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00040869" target="_blank" >RIV/00216224:14110/10:00040869 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

čeština

Original language name

Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology

Original language description

PURPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS: The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients(32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16).

Czech name

Tectonic penetrating keratoplasty and sclerokeratoplasty as treatment for perforated corneal ulcers of different aetiology

Czech description

PURPOSE: To report the clinical outcomes in patient with herpetic, bacterial and autoimmune corneal ulcers treated by tectonic, centric or eccentric penetrating keratoplasty or by tectonic sclerokeratoplasty. DESIGN: Nonrandomized clinical trial. METHODS: The study included 37 patients (37 eyes) with perforated corneal ulcers consecutively operated by two surgeons. The main patients age was 62 years (SD 7). The patients were divided into 3 groups. Group A - keratolysis in herpes eye disease, 12 patients(32%), group B - keratolysis in autoimmune diseases (rheumatoid arthritis, Wegener granulomatosis 14 patients (37%) and group C - keratolysis in bacterial corneal ulcers 11 patients (31%). The time of observation was 12 to 42 months (SD 28). BCVA and immunologic graft rejection was assessed after 3 months. All patients have used systemic immunosupression CSA and MFM during 12 to 32 months(median 16).

Type

O - Miscellaneous

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

<a href="/en/project/NR8507" target="_blank" >NR8507: DNA diagnostics of bacterial and viral infections of the cornea</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů