Extractions of isoquinoline alkaloids with butanol and octanol

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00044574" target="_blank" >RIV/00216224:14110/10:00044574 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Extractions of isoquinoline alkaloids with butanol and octanol

Original language description

Six isoquinoline alkaloids of different structural types (sanguinarine, chelerythrine, berberine, coptisine, allocryptopine, protopine) were extracted by butanol and octanol from aqueous solution, pH 4.5. The aqueous phase was analysed by HPLC before andafter extraction. Extraction by butanol was non-selective, alkaloids passed into organic phase in 83-98 %. Octanol extraction provided more selective yields: sanguinarine 99 %, chelerythrine 94 %, berberine 18 %, coptisine 16 %, allocryptopine 7.5 %, protopine 7 %. Further, we tested octanol treatment of real plant extract from Dicranostigma lactucoides. The octanol extraction yields were again selective: sanguinarine 98 %, chelerythrine 92 %, chelirubine 92.5 %, protopine 6 % and allocryptopine 3.5 %.6-Butoxy-5,6-dihydrosanguinarine and 6-butoxy-5,6-dihydrochelerythrine were prepared and their NMR and MS data are reported and discussed.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

<a href="/en/project/GA525%2F08%2F0819" target="_blank" >GA525/08/0819: Plant sources of minor benzophenanthridine alkaloids and study of their interaction with DNA</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Fitoterapia

ISSN

0367-326X

e-ISSN

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Volume of the periodical

81

Issue of the periodical within the volume

6

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

4

Pages from-to

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UT code for WoS article

000281073800021

EID of the result in the Scopus database

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