The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00046774" target="_blank" >RIV/00216224:14110/10:00046774 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus.

Original language description

We studied whether the cognitive event-related potentials (ERP) in the subthalamic nucleus (STN) are modified by the modulation of the inferior frontal cortex (IFC) and the dorsolateral prefrontal cortex (DLPFC) with repetitive transcranial magnetic stimulation (rTMS). Eighteen patients with Parkinson disease who had been implanted with a deep brain stimulation (DBS) electrode were included in the study. The ERPs were recorded from the DBS electrode before and after the rTMS (1 Hz, 600 pulses) over either the right IFC (10 patients) or right DLPFC (8 patients). rTMS over the right IFC led to a shortening of ERP latencies from 277 ms (SD) to 252 ms in the standard protocol and from 296 ms to 270 ms in the protocol modified by a higher load of executivefunctions. Connections (the IFC-STN hyperdirect pathway) with the cortex that bypass the BG-thalamocortical circuitries could explain the position of the STN in the processing of executive functions.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Experimental Brain Research

ISSN

0014-4819

e-ISSN

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Volume of the periodical

203/2010

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

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UT code for WoS article

000277712500008

EID of the result in the Scopus database

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