Natriuretic Peptides As A Marker of Left Ventricular Diastolic Dysfunction in Patients With Obesity and Hypertension: Relationship With Doppler Tissue Imaging
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00046870" target="_blank" >RIV/00216224:14110/10:00046870 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
čeština
Original language name
Natriuretic Peptides As A Marker of Left Ventricular Diastolic Dysfunction in Patients With Obesity and Hypertension: Relationship With Doppler Tissue Imaging
Original language description
Natriuretic peptide (NP) increased early in patients with left ventricular (LV) systolic dysfunction, but early markers of HF development in patients with obesity and hypertension (HT) and LV diastolic dysfunction (DD) are already not very well known. Methods: 118 (56 years, 62 men) consecutive HT pts (stage I and II) with obesity using the value of 30 of body mass Index (BMI) as a cut-off was divided into two groups: A with BMI<30 (n = 56) and B with BMI>30 (n = 62). LV function was assessed by natriuretic peptide plasma levels (BNP, NT pro BNP). Relative wall thickness, cardiac mass, LV volumes and ejection fraction, velocity of early and late diastolic LV filling maximal velocity (E, A), E/A ratio, deceleration E time from transmitral Doppler,and pulsed doppler tissue imaging of velocities of mitral annular movements (Sm, Em, Am) were calculated by echo. Results: Pts revealed normal systolic function of the LV and the same degrese of LVH (61,19 versus 63,4 g/m2,7).
Czech name
Natriuretic Peptides As A Marker of Left Ventricular Diastolic Dysfunction in Patients With Obesity and Hypertension: Relationship With Doppler Tissue Imaging
Czech description
Natriuretic peptide (NP) increased early in patients with left ventricular (LV) systolic dysfunction, but early markers of HF development in patients with obesity and hypertension (HT) and LV diastolic dysfunction (DD) are already not very well known. Methods: 118 (56 years, 62 men) consecutive HT pts (stage I and II) with obesity using the value of 30 of body mass Index (BMI) as a cut-off was divided into two groups: A with BMI<30 (n = 56) and B with BMI>30 (n = 62). LV function was assessed by natriuretic peptide plasma levels (BNP, NT pro BNP). Relative wall thickness, cardiac mass, LV volumes and ejection fraction, velocity of early and late diastolic LV filling maximal velocity (E, A), E/A ratio, deceleration E time from transmitral Doppler,and pulsed doppler tissue imaging of velocities of mitral annular movements (Sm, Em, Am) were calculated by echo. Results: Pts revealed normal systolic function of the LV and the same degrese of LVH (61,19 versus 63,4 g/m2,7).
Classification
Type
O - Miscellaneous
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů