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Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00051692" target="_blank" >RIV/00216224:14110/10:00051692 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1056/NEJMoa1001121" target="_blank" >http://dx.doi.org/10.1056/NEJMoa1001121</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1056/NEJMoa1001121" target="_blank" >10.1056/NEJMoa1001121</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events

  • Original language description

    It is not known whether drugs that block the renin-angiotensin system reduce the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance. METHODS In this double-blind, randomized clinical trial with a 2-by-2 factorial design, we assigned 9306 patients with impaired glucose tolerance and established cardiovascular disease or cardiovascular risk factors to receive valsartan (up to 160 mg daily) or placebo (and nateglinide or placebo) in addition to lifestyle modification. Wethen followed the patients for a median of 5.0 years for the development of diabetes (6.5 years for vital status).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    New England Journal of Medicine

  • ISSN

    0028-4793

  • e-ISSN

  • Volume of the periodical

    362

  • Issue of the periodical within the volume

    16

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    1477-1490

  • UT code for WoS article

    000276894700007

  • EID of the result in the Scopus database