Clinicopathologic features of histiocytic lesions following ALL, with a review of the literature.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00051768" target="_blank" >RIV/00216224:14110/10:00051768 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2350/09-03-0622-OA.1" target="_blank" >http://dx.doi.org/10.2350/09-03-0622-OA.1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2350/09-03-0622-OA.1" target="_blank" >10.2350/09-03-0622-OA.1</a>
Alternative languages
Result language
angličtina
Original language name
Clinicopathologic features of histiocytic lesions following ALL, with a review of the literature.
Original language description
We describe the clinicopathologic features of 15 patients who had histiocytic lesions that followed acute lymphoblastic leukemia (ALL). Twenty-one separate histiocytic lesions were evaluated that covered a wide spectrum, some conforming to the usual categories of juvenile xanthogranulomas (5), Langerhans' cell histiocytosis (1), Langerhans' cell sarcoma (4), Rosai-Dorfman disease (1), and histiocytic sarcoma (4). Most were atypical for the category by histology, phenotype, or abnormally high turnover rate. Seven low-grade lesions defied easy categorization and were characterized only as "atypical histiocytic lesion" following ALL. For those evaluated, the molecular signature of the prior leukemia was present in the histiocytic lesion. In 3 of 15 patients, the leukemia and histiocytic lesion shared immunoglobulin H or monoclonal TCR gene rearrangements and, in 4 of 15 patients, clonal identity was documented by fluorescence in situ hybridization.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FG - Paediatrics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric and Developmental Pathology
ISSN
1093-5266
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
225-237
UT code for WoS article
000280500400008
EID of the result in the Scopus database
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