Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F10%3A00051810" target="_blank" >RIV/00216224:14110/10:00051810 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/10:#0000250

Result on the web

<a href="http://dx.doi.org/10.1136/oem.2009.046839" target="_blank" >http://dx.doi.org/10.1136/oem.2009.046839</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/oem.2009.046839" target="_blank" >10.1136/oem.2009.046839</a>

Result language

angličtina

Original language name

Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study

Original language description

To investigate the role of occupational exposure to organic solvents in the aetiology of B-cell non-Hodgkin's lymphoma (B-NHL) and its major subtypes, as well as Hodgkin's lymphoma and T-cell lymphoma. Methods 2348 lymphoma cases and 2462 controls participated in a case-control study in six European countries. A subset of cases were reviewed by a panel of pathologists to ensure diagnostic consistency. Exposure to solvents was assessed by industrial hygienists and occupational experts based on a detailedoccupational questionnaire. Results Risk of follicular lymphoma significantly increased with three independent metrics of exposure to benzene, toluene and xylene (BTX) (combined p = 4 x 10(-7)) and to styrene (p = 1 x 10(-5)), and chronic lymphocytic leukaemia (CLL) risk increased with exposure to solvents overall (p = 4 x 10(-6)), BTX (p = 5 x 10(-5)), gasoline (p = 8 x 10(-5)) and other solvents (p = 2 x 10(-6)). Risk of B-NHL for ever exposure to solvents was not elevated (OR = 1.1,

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Occupational and environmental medicine

ISSN

1351-0711

e-ISSN

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Volume of the periodical

67

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

341-347

UT code for WoS article

000277383300012

EID of the result in the Scopus database

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