Interferon-gamma +874A/T polymorphism in relation to generalized chronic periodontitis and the presence of periodontopathic bacteria

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00051442" target="_blank" >RIV/00216224:14110/11:00051442 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/11:#0000644

Result on the web

<a href="http://dx.doi.org/10.1016/j.archoralbio.2010.09.005" target="_blank" >http://dx.doi.org/10.1016/j.archoralbio.2010.09.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.archoralbio.2010.09.005" target="_blank" >10.1016/j.archoralbio.2010.09.005</a>

Result language

angličtina

Original language name

Interferon-gamma +874A/T polymorphism in relation to generalized chronic periodontitis and the presence of periodontopathic bacteria

Original language description

Interferon gamma (IFN-gamma) is one of the key regulatory cytokines that has a significant effect on immune responses. It may be important in the chronic inflammatory diseases such as periodontitis in which increased IFN-gamma levels were found. The aimof this study was to analyze +874A/T polymorphism in the IFN-gamma gene and its associations with the presence of periodontopathic bacteria and susceptibility to generalized chronic periodontitis (CP). Our results showed no differences in the allele andgenotype frequencies of the IFN-gamma +874A/T polymorphism between patients with CP and controls (p&lt;0.05). Although we found significant differences in the occurrence of periodontal bacteria between patients with CP and healthy controls (from p&lt;0.00001 to p&lt;0.05), no significant association between IFN-gamma +874A/T polymorphism and periodontal pathogens was observed in any group.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Oral Biology

ISSN

0003-9969

e-ISSN

—

Volume of the periodical

56

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

153-158

UT code for WoS article

000287465500007

EID of the result in the Scopus database

—