Wallerian degeneration and peripheral nerve conditions for both axonal regeneration and neuropathic pain induction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00053051" target="_blank" >RIV/00216224:14110/11:00053051 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.aanat.2011.02.011" target="_blank" >http://dx.doi.org/10.1016/j.aanat.2011.02.011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aanat.2011.02.011" target="_blank" >10.1016/j.aanat.2011.02.011</a>

Result language

angličtina

Original language name

Wallerian degeneration and peripheral nerve conditions for both axonal regeneration and neuropathic pain induction

Original language description

Wallerian degeneration is a cascade of stereotypical events in reaction to injury of nerve fibres. These events consist of cellular and molecular alterations, including macrophage invasion, activation of Schwann cells, as well as neurotrophin and cytokine upregulation. This review focuses on cellular and molecular changes distal to various types of peripheral nerve injury which simultaneously contribute to axonal regeneration and neuropathic pain induction. In addition to the stereotypical events of Wallerian degeneration, various types of nerve damage provide different conditions for both axonal regeneration and neuropathic pain induction. Wallerian degeneration of injured peripheral nerve is associated with an inflammatory response including rapid upregulation of the immune signal molecules like cytokines, chemokines and transcription factors with both beneficial and detrimental effects on nerve regeneration or neuropathic pain induction.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Anatomy

ISSN

0940-9602

e-ISSN

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Volume of the periodical

193

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

267-275

UT code for WoS article

000294520800004

EID of the result in the Scopus database

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