Expression and characterization of c-Myb in prenatal odontogenesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00053073" target="_blank" >RIV/00216224:14110/11:00053073 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/11:00368272
Result on the web
<a href="http://dx.doi.org/10.1111/j.1440-169X.2011.01287.x" target="_blank" >http://dx.doi.org/10.1111/j.1440-169X.2011.01287.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1440-169X.2011.01287.x" target="_blank" >10.1111/j.1440-169X.2011.01287.x</a>
Alternative languages
Result language
angličtina
Original language name
Expression and characterization of c-Myb in prenatal odontogenesis
Original language description
The transcription factor c-Myb is involved in the control of cell proliferation, survival and differentiation. As these processes accompany the morphogenesis of developing teeth, this work investigates the possible role of c-Myb during odontogenesis. Analysis of the expression of c-Myb in the monophyodont mouse was followed by similar analysis in a diphyodont species, the pig, which has a dentition more closely resembling that of the human. The distribution of c-Myb was correlated with the pattern of proliferation and apoptosis and the tooth phenotype of c-Myb mutant mice was also assessed. In the mouse, c-Myb expression was detected throughout prenatal development of the first molar tooth. Negative temporospatial correlation was found between c-Myb expression and apoptosis, while c-Myb expression positively correlated with proliferation. c-Myb-positive cells, however, were more abundant than the proliferating cell nuclear antigen positive cells, suggesting other roles of c-Myb in odon
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Development, Growth and Differentiation
ISSN
0012-1592
e-ISSN
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Volume of the periodical
53
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
793-803
UT code for WoS article
000293902200004
EID of the result in the Scopus database
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