The Neural Substrate of Predictive Motor Timing in Spinocerebellar Ataxia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00053159" target="_blank" >RIV/00216224:14110/11:00053159 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s12311-010-0237-y" target="_blank" >http://dx.doi.org/10.1007/s12311-010-0237-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12311-010-0237-y" target="_blank" >10.1007/s12311-010-0237-y</a>
Alternative languages
Result language
angličtina
Original language name
The Neural Substrate of Predictive Motor Timing in Spinocerebellar Ataxia
Original language description
The neural mechanisms involved in motor timing are subcortical, involving mainly cerebellum and basal ganglia. However, the role played by these structures in predictive motor timing is not well understood. Unlike motor timing, which is often tested using rhythm production tasks, predictive motor timing requires visuo-motor coordination in anticipation of a future event, and it is evident in behaviors such as catching a ball or shooting a moving target. We examined the role of the cerebellum and striatum in predictive motor timing in a target interception task in healthy (n = 12) individuals and in subjects (n = 9) with spinocerebellar ataxia types 6 and 8. The performance of the healthy subjects was better than that of the spinocerebellar ataxia. Successful performance in both groups was associated with increased activity in the cerebellum (right dentate nucleus, left uvula (lobule V), and lobule VI), thalamus, and in several cortical areas.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cerebellum
ISSN
1473-4222
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
233-244
UT code for WoS article
000291601100008
EID of the result in the Scopus database
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