Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00053819" target="_blank" >RIV/00216224:14110/11:00053819 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/11:#0001225
Result on the web
<a href="http://dx.doi.org/10.1016/j.ijid.2011.09.011" target="_blank" >http://dx.doi.org/10.1016/j.ijid.2011.09.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijid.2011.09.011" target="_blank" >10.1016/j.ijid.2011.09.011</a>
Alternative languages
Result language
angličtina
Original language name
Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance
Original language description
We evaluated the performance of a galactomannan (GM) assay in bronchoalveolar lavage (BAL) fluid compared to serum samples for the diagnosis of invasive pulmonary aspergillosis (IPA) in patients with hematological diseases. Results: Twenty-eight cases ofIPA (11%) were diagnosed. The highest sensitivity (78.6%) with good specificity (98.6%) was obtained with a triple detection of GM in bronchial, alveolar, and serum samples. Neutropenia and antifungal therapy for only 24 h increased the sensitivity, while antifungal treatment for more than 2 days decreased assay performance.Conclusions: In contrast to recently published data, we found only moderate sensitivity, but high specificity and high positive predictive value of the detection of GM in BAL fluid.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Infectious Diseases
ISSN
1201-9712
e-ISSN
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Volume of the periodical
15
Issue of the periodical within the volume
12
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
"e874"-"e881"
UT code for WoS article
000298114700014
EID of the result in the Scopus database
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