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Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00053819" target="_blank" >RIV/00216224:14110/11:00053819 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/11:#0001225

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.ijid.2011.09.011" target="_blank" >http://dx.doi.org/10.1016/j.ijid.2011.09.011</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ijid.2011.09.011" target="_blank" >10.1016/j.ijid.2011.09.011</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance

  • Original language description

    We evaluated the performance of a galactomannan (GM) assay in bronchoalveolar lavage (BAL) fluid compared to serum samples for the diagnosis of invasive pulmonary aspergillosis (IPA) in patients with hematological diseases. Results: Twenty-eight cases ofIPA (11%) were diagnosed. The highest sensitivity (78.6%) with good specificity (98.6%) was obtained with a triple detection of GM in bronchial, alveolar, and serum samples. Neutropenia and antifungal therapy for only 24 h increased the sensitivity, while antifungal treatment for more than 2 days decreased assay performance.Conclusions: In contrast to recently published data, we found only moderate sensitivity, but high specificity and high positive predictive value of the detection of GM in BAL fluid.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Infectious Diseases

  • ISSN

    1201-9712

  • e-ISSN

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    "e874"-"e881"

  • UT code for WoS article

    000298114700014

  • EID of the result in the Scopus database