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Fast brain-wide search of highly discriminative regions in medical images: an application to Alzheimer's disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00056978" target="_blank" >RIV/00216224:14110/11:00056978 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fast brain-wide search of highly discriminative regions in medical images: an application to Alzheimer's disease

  • Original language description

    We propose a fast algorithm for the identification of localised brain regions from medical images that discriminate between two groups of individuals. The method is based on a combination of penalised regression and a data resampling procedure. We applythis approach to both MRI and PET images for the classification of subjects with Alzheimer's disease and mild cognitive impairment. We show that the voxels selected by the algorithm form connected brain regions which are well known to be affected by Alzheimer's disease. A linear statistical classifier trained on the selected voxels achieves cross-validated classification results that are comparable to those obtained by current state-of-the-art methodologies.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceedings of Medical Image Understanding and Analysis 2011

  • ISBN

    1-901725-41-3

  • ISSN

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    17-21

  • Publisher name

    King's College London

  • Place of publication

    London, United Kingdom

  • Event location

    King's College London, UK

  • Event date

    Jul 13, 2011

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article