Haplotypes of the IL-1 Gene Cluster are Associated With Gastroesophageal Reflux Disease and Barrett?s Esophagusin the Czech Population
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00059002" target="_blank" >RIV/00216224:14110/11:00059002 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Haplotypes of the IL-1 Gene Cluster are Associated With Gastroesophageal Reflux Disease and Barrett?s Esophagusin the Czech Population
Original language description
Gastroesophageal reflux (GERD) is a major public health problem in the Western world that can lead to a number of complications, such as reflux esophagitis (RE), Barrett?s esophagus (BE), and adenocarcinoma. It has been postulated that a strong pro-inflammatory host response predisposes to disease. Although no significant role of single IL-1 variants in reflux disease was found, our results indicate that IL-1 haplotypes may be associated with susceptibility to GERD and Barrett?s esophagus.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/2B06060" target="_blank" >2B06060: Increasing the efficacy of the diagnostics and treatment of gastro-esophageal reflux disease.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů