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Measuring diffuse metabolic activity on FDG-PET/CT: new method for evaluating Langerhans cell histiocytosis activity in pulmonary parenchyma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00059813" target="_blank" >RIV/00216224:14110/12:00059813 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/12:#0000917

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.nucmedbio.2011.10.002" target="_blank" >http://dx.doi.org/10.1016/j.nucmedbio.2011.10.002</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.nucmedbio.2011.10.002" target="_blank" >10.1016/j.nucmedbio.2011.10.002</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Measuring diffuse metabolic activity on FDG-PET/CT: new method for evaluating Langerhans cell histiocytosis activity in pulmonary parenchyma

  • Original language description

    Pulmonary Langerhans cell histiocytosis (PLCH) is a rare cause of interstitial lung disease characterized by formation of nodules in the active phase of the disease that evolve into nonactive cystic lesions later on. To evaluate PLCH activity in patients, we developed a new method for measuring diffuse metabolic activity on fluorine-18-fluorodeoxyglucose positron emission tomography/ computed tomography (FDG-PET/CT) using a lung-to-liver activity ratio. Material and Methods: We retrospectively studied aseries of 4 FDG-PET and 23 FDG-PET/CT scans from 7 patients with PLCH and analyzed a sample of 100 randomly chosen FDG-PET/CT studies free from any known lung or hepatic diseases. Maximum standardized uptake value (SUVmax) in a spherical volume (6?8 cmin diameter) in the right lung was put into relation with SUVmax in a spherical volume (9?10 cm in diameter) in the reference liver parenchyma to set up the SUVmaxPULMO/SUVmaxHEPAR index.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nuclear Medicine and Biology

  • ISSN

    0969-8051

  • e-ISSN

  • Volume of the periodical

    39

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    429-436

  • UT code for WoS article

    000301961700012

  • EID of the result in the Scopus database