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RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060402" target="_blank" >RIV/00216224:14110/12:00060402 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023728:_____/12:#0002053

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.molimm.2012.06.006" target="_blank" >http://dx.doi.org/10.1016/j.molimm.2012.06.006</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.molimm.2012.06.006" target="_blank" >10.1016/j.molimm.2012.06.006</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis

  • Original language description

    The MCP-1/CCL2 as well as RANTES/CCL5 chemokines are potent chemoattractants involved in immunoregulatory and inflammatory processes of rheumatoid arthritis. Recent studies demonstrated elevated levels of MCP-1 and RANTES in plasma, synovial fluid, and the synovial tissue of patients with RA. To examine the relationship among MCP-1 and RANTES single nucleotide polymorphisms and circulating levels and rheumatoid arthritis (RA), a total of 156 RA patients and 125 controls were recruited into the study. Anassociation of -855 C/G MCP-1 polymorphism to IgM RF within the RA patients was observed. The lowest circulating levels of RANTES were observed in the AA variant of RANTES -403 G/A polymorphism. Furthermore, an association of -403 AA variant to circulating levels of IL-15 and IL-10 was found.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Molecular Immunology

  • ISSN

    0161-5890

  • e-ISSN

  • Volume of the periodical

    52

  • Issue of the periodical within the volume

    3-4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    273-278

  • UT code for WoS article

    000307489800023

  • EID of the result in the Scopus database