RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060402" target="_blank" >RIV/00216224:14110/12:00060402 - isvavai.cz</a>
Alternative codes found
RIV/00023728:_____/12:#0002053
Result on the web
<a href="http://dx.doi.org/10.1016/j.molimm.2012.06.006" target="_blank" >http://dx.doi.org/10.1016/j.molimm.2012.06.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.molimm.2012.06.006" target="_blank" >10.1016/j.molimm.2012.06.006</a>

Result language
angličtina
Original language name
RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis
Original language description
The MCP-1/CCL2 as well as RANTES/CCL5 chemokines are potent chemoattractants involved in immunoregulatory and inflammatory processes of rheumatoid arthritis. Recent studies demonstrated elevated levels of MCP-1 and RANTES in plasma, synovial fluid, and the synovial tissue of patients with RA. To examine the relationship among MCP-1 and RANTES single nucleotide polymorphisms and circulating levels and rheumatoid arthritis (RA), a total of 156 RA patients and 125 controls were recruited into the study. Anassociation of -855 C/G MCP-1 polymorphism to IgM RF within the RA patients was observed. The lowest circulating levels of RANTES were observed in the AA variant of RANTES -403 G/A polymorphism. Furthermore, an association of -403 AA variant to circulating levels of IL-15 and IL-10 was found.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
—

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)