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Positron Emission Tomography and Clinical Predictors of Survival in Primary Extragonadal Germ Cell Tumors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060596" target="_blank" >RIV/00216224:14110/12:00060596 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/12:8426 RIV/00064203:_____/12:8426 RIV/00064190:_____/12:#0000363

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Positron Emission Tomography and Clinical Predictors of Survival in Primary Extragonadal Germ Cell Tumors

  • Original language description

    Primary extragonadal germ cell tumors (EGTs) are an uncommon malignancy accounting for 2?4% of all germ cell neoplasms in adult males. Their prognosis is worse than that for testicular germ cell tumors because of their relative chemoresistance and frequent presentation with widely disseminated metastases. We have studied the role of fluorodeoxyglucose positron emission tomography (FDG-PET) for outcome prediction of patients with EGTs. Patients and Methods: We have retrospectively analysed 36 men with germ cell tumors originating in the mediastinum or the retroperitoneum. All patients were treated between 1994 and 2010. Negative result of testicular ultrasonographic examination and/or testicular biopsy was required for diagnosis of EGT. Platinum-based systemic therapy was used in all cases, and resectable residual tumor masses were removed surgically. Results: Overall survival at one and three years was 81% (95% confidence interval [CI]: 68?94%) and 55% (CI: 38?71%), respectively.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Klinická onkologie

  • ISSN

    0862-495X

  • e-ISSN

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    178-183

  • UT code for WoS article

  • EID of the result in the Scopus database