Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00061311" target="_blank" >RIV/00216224:14110/12:00061311 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients

Original language description

In this study we tested whether joint evaluation of the frequency (fcs) at which maxima of power in the cross-spectra between the variability in systolic blood pressure and inter-beat intervals in the range of 0.06-0.12 Hz occur together with the quantification of baroreflex sensitivity (BRS) may improve early detection of autonomic dysfunction in type 1 diabetes mellitus (T1DM). We measured 14 T1DM patients (age 20.3-24.2 years, DM duration 10.4-14.2 years, without any signs of autonomic neuropathy) and 14 age-matched controls (Co). Finger arterial blood pressure was continuously recorded by Finapres for one hour. BRS and fcs were determined by the spectral method. Receiver-operating curves (ROC) were calculated for fcs, BRS, and a combination of bothfactors determined as F(z)=1/(1+exp(-z)), z=3.09?0.013*BRS? 0.027*fcs. T1DM had significantly lower fcs than Co (T1DM: 88.8plusminus 6.7 vs. Co: 93.7plusminus 3.8 mHz; p&lt;0.05), and a tendency towards lower BRS compared to Co (T1DM: 10

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

—

Volume of the periodical

61

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

347-354

UT code for WoS article

000309194600002

EID of the result in the Scopus database

—