A new F-actin structure in fungi: actin ring formation around the cell nucleus of Cryptococcus neoformans

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00065948" target="_blank" >RIV/00216224:14110/13:00065948 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/jmicro/dfs074" target="_blank" >http://dx.doi.org/10.1093/jmicro/dfs074</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/jmicro/dfs074" target="_blank" >10.1093/jmicro/dfs074</a>

Result language
angličtina
Original language name
A new F-actin structure in fungi: actin ring formation around the cell nucleus of Cryptococcus neoformans
Original language description
The F-actin cytoskeleton of Cryptococcus neoformans is known to comprise actin cables, cortical patches and cytokinetic ring. Here, we describe a new F-actin structure in fungi, a perinuclear F-actin collar ring around the cell nucleus, by fluorescent microscopic imaging of rhodamine phalloidin-stained F-actin. Perinuclear F-actin rings form in Cryptococcus neoformans treated with the microtubule inhibitor Nocodazole or with the drug solvent dimethyl sulfoxide (DMSO) or grown in yeast extract peptone dextrose (YEPD) medium, but they are absent in cells treated with Latrunculin A. Perinuclear F-actin rings may function as ?funicular cabin? for the cell nucleus, and actin cables as intracellular ?funicular? suspending nucleus in the central position in the cell and moving nucleus along the polarity axis along actin cables.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/GA310%2F06%2F0605" target="_blank" >GA310/06/0605: Human pathogenic fungi : the cytoskeleton as a potential target of inhibition of morphogenesis.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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