Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00068403" target="_blank" >RIV/00216224:14110/13:00068403 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/13:#0002058

Result on the web

<a href="http://dx.doi.org/10.3324/haematol.2012.070235" target="_blank" >http://dx.doi.org/10.3324/haematol.2012.070235</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3324/haematol.2012.070235" target="_blank" >10.3324/haematol.2012.070235</a>

Result language

angličtina

Original language name

Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse

Original language description

Based on molecular aberrations, in particular the NPM1 mutation (NPM1mut) and the FLT3 internal tandem duplication (Flt3-ITD), prognostic subgroups have been defined among patients with acute myeloid leukemia with normal karyotype. Whereas these subgroups are known to play an important role in outcome in first complete remission, and also in the indication for allogeneic stem cell transplantation, data are limited on their role after transplantation in advanced disease. To evaluate the role of molecularsubgroups of acute myeloid leukemia with normal karyotype after allogeneic stem cell transplantation beyond first complete remission, we analyzed the data from 141 consecutive adults (median age: 51.0 years, range 18.4-69.3 years) who had received an allogeneic transplant either in primary induction failure or beyond first complete remission.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Haematologica/the hematology journal

ISSN

0390-6078

e-ISSN

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Volume of the periodical

Vol. 98

Issue of the periodical within the volume

4

Country of publishing house

IT - ITALY

Number of pages

8

Pages from-to

518-525

UT code for WoS article

000319897700015

EID of the result in the Scopus database

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