Trefoil factor 2 expression and its significance as a predictor of severity of sepsis in children
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00068502" target="_blank" >RIV/00216224:14110/13:00068502 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.peptides.2013.04.011" target="_blank" >http://dx.doi.org/10.1016/j.peptides.2013.04.011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.peptides.2013.04.011" target="_blank" >10.1016/j.peptides.2013.04.011</a>
Alternative languages
Result language
angličtina
Original language name
Trefoil factor 2 expression and its significance as a predictor of severity of sepsis in children
Original language description
Intestinal injury significantly contributes to critical illness, sepsis and multiorgan failure. TFF2 (Trefoil Factor 2) is expressed and secreted preferentially by gastric mucous neck cells. TFF2 gene expression is promptly increased after gut injury, and its expression profile broadens to include the regenerative epithelia of virtually the entire gastrointestinal tract. The first objective of our study was an analysis of TFF2 levels dynamics in patients with Systemic Inflammatory Response Syndrome (SIRS) or septic condition during a 5-day period after admission. The second objective was to determine optimal cut-off value and quantify diagnostic characteristics of TFF2 between controls and patients with various septic states. The study included 57 children aged 0-19 years, with expected or proven SIRS and septic condition. The degree of severity was evaluated according to PELOD Score (Pediatric Logistic Organ Dysfunction).
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Peptides
ISSN
0196-9781
e-ISSN
—
Volume of the periodical
46
Issue of the periodical within the volume
August
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
1-5
UT code for WoS article
000322628600001
EID of the result in the Scopus database
—